Allergen immunotherapy, also known as “desensitisation” is the only allergy treatment which acts directly on the immune system in order to rebalance it.

By inducing increased tolerance of allergensallergen immunotherapy is therefore the only solution capable of offering lasting treatment for allergic conditions.  Allergen immunotherapy significantly reduces allergy symptoms and the use of symptomatic treatments. Moreover, it provides long-term effects[1].

Allergen immunotherapy is offered to patients (from the age of five) suffering from a respiratory allergy and for whom symptomatic treatments prove insufficient or are poorly tolerated.

Allergen immunotherapy: how does it work?

Only an allergy specialist can prescribe an allergen immunotherapy treatment following an accurate diagnosis.

Allergen immunotherapy is a targeted treatment involving administering progressively larger doses of allergen extracts to the patient, which will reduce the immune system’s hyper-reactivity and the resulting inflammation.

The treatment may be administered sublingually (solutions or tablets (for grass pollen allergy)[2] to be placed under the tongue) or subcutaneously (injections in the arm performed in a medical setting).

In the case of seasonal allergies such as pollen allergy, treatment may be taken intermittently (only taken during certain months of the year). In such cases, it is necessary to begin the treatment prior to the start of the pollen season. In the case of perennial allergies, such as an allergy to house dust mites or animal hair, treatment continues throughout the year.

In order to be effective in the long-term, allergen immunotherapy treatment lasts between three and five consecutive seasons[3].


[1]  Jacobsen L. et al. Specific immunotherapy has long-term preventive effect of seasonal and perennial asthma: 10-year follow-up on the PAT study. Allergy. 2007 Aug;62(8):943-8.

[2] Only available for grass pollen allergy 

[3] Marogna M. et al., Long-lasting effects of sublingual immunotherapy according to its duration: A 15-year study. J Allergy Clin Immunology, 2010

Stallergenes Greer UK